2024 Statins in elderly nejm

Statins in elderly nejm

Author: jntt

August undefined, 2024

WebThe final decision on the therapeutic strategy with statins in elderlies at higher risk to develop cardiovascular events should be always based on a careful analysis of the patient's general health and on the presence of metabolic abnormalities or drug interactions potentially leading to risk. Keywords: WebImportance Data are limited regarding statin therapy for primary prevention of atherosclerotic cardiovascular disease (ASCVD) in adults 75 years and older.. Objective …

Overuse of Statins in Older Adults AAFP

WebFeb 10, 2024 · Statins are frequently initiated in patients aged 80 years and older after an ischemic stroke, even though evidence on prevention of recurrent cardiovascular disease … WebJun 22, 2024 · Results: Of the 18,846 participants, 5,898 (31.3%) were taking statins at baseline. At baseline, statin users were more likely than nonusers to be women, to have <12 years’ education, and to have obesity, chronic kidney disease, diabetes, and hypertension. sjmc home login

Research Supports Statins in the Elderly - hcplive.com

WebFeb 2, 2024 · Statin therapy produces significant reductions in major vascular events irrespective of age, but there is less direct evidence of benefit among patients older than 75 years who do not already have evidence of occlusive vascular disease. This limitation is now being addressed by further trials. Funding WebMay 24, 2024 · Statins are drugs that can be helpful in lowering LDL (“bad”) cholesterol. But statin side effects like liver damage and memory issues can also occur. Your doctor can help you weigh the pros... WebOct 30, 2024 · Treatment with Statins in Elderly Patients Authors Ruxandra-Nicoleta Horodinschi 1 2 , Ana Maria Alexandra Stanescu 3 , Ovidiu Gabriel Bratu 4 5 , Anca Pantea … sutliff tobacco.com

Statin Use Not Tied to Dementia Risk in Older Patients

Relieving treatment-resistant depression in older adults

WebFeb 13, 2024 · Data from recent clinical trials of statins indicate that the elderly patients with the highest cardiovascular risk are likely to derive the most benefits from cholesterol … WebFeb 13, 2024 · Another Study of Cholesterol in Older Patients Allan S. Brett, MD, reviewing Maihofer AX et al. J Am Geriatr Soc 2024 Feb High LDL cholesterol levels, measured after … sutliff ts24WebJul 22, 2024 · Efforts to balance the benefit and harm of statin use among older adults with life-limiting illness and further deprescribe statins and inappropriate medications in the nursing home are warranted. 3; Editor's Note: Commentary based on Mack DS, Tjia J, Hume AL, Lapane KL. Prevalent statin use in long-stay nursing home residents with life ... sutliff tobacco products

"WebWhile these guidelines were largely derived from the same body of evidence, recommendations for older adults are discordant, highlighting the limitations, variability and ambiguity in the existing data [3, 10, 20].We present key updates in the 2024 AHA/ACC Cholesterol Guidelines [] and 2024 ACC/AHA Primary Prevention Guidelines [] and the … " - Statins in elderly nejm

Statins in elderly nejm

Statins After Ischemic Stroke in the Oldest Stroke

WebOct 1, 2024 · In patients age 75 and younger, the efficacy of statins for primary prevention is well-established on the basis of multiple randomized trials, which have found that they reduce the relative risk of major vascular events by 20-30%. 2,3 Given the paucity of adults … WebJul 12, 2024 · Participants' median age was 74 years, and 56% were women. With 85,557 person-years of follow-up, the investigators identified 566 incident cases of dementia. …

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WebMay 10, 2012 · Over a period of 4 years of statin use, a reduction of 1 mmol per liter (39 mg per deciliter) in the level of low-density lipoprotein (LDL) cholesterol translates into a 9% … WebApr 12, 2024 · Moderate-intensity statin with ezetimibe combination therapy was associated with lower rates of intolerance-related drug discontinuation or dose reduction among …

WebJACC, April 11 2024 The routine use of high-intensity statins should be considered carefully in elderly patients because of their higher risk of intolerance… Samir Redzepagic على LinkedIn: Combination Moderate-Intensity Statin and Ezetimibe Therapy for Elderly… WebAug 31, 2024 · Statins are generally well-tolerated and safe drugs to lower low-density lipoprotein cholesterol levels and consequently lower ASCVD risk. 5 Statins rank among the most studied drug classes: half of the middle-aged population without ASCVD would have been eligible for at least one of the many randomized trials demonstrating the …

WebJACC, Feb 2024 It is unclear whether elevated low-density lipoprotein (LDL) triglycerides are associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD). WebNegative Impact of High Cholesterol. Studying cholesterol in older adults is trickier than it sounds, Martin says. Many people who have high cholesterol die from complications of heart disease before reaching an advanced age. Those who live into their 70s or 80s despite high cholesterol might have other factors that increased their longevity.

WebJul 12, 2024 · Some studies suggest that statins may preserve cognitive function, while others suggest the possibility of harmful neurocognitive effects. Investigators leveraged comprehensive cognitive data collected in an aspirin trial to conduct an observational study of statins and cognitive function.

WebOct 2, 2024 · Statin drugs have been shown to reduce the risk of cardiovascular disease (CVD) in young and middle-aged adults. With older adults (those 75 and over), the benefits … sutliff \u0026 stout annual scholarship contestWebMay 12, 2024 · Methods and Results. A population‐based cohort study consisting of 19 544 post‐acute coronary syndrome statin‐users aged ≥66 years between January 1, 2024 and March 31, 2014 was used to project the number of adverse outcome events (acute myocardial infarction or death from any cause) that could be prevented if all post‐acute … sutliff trucking incWebStatin therapy lowers the risk of cardiovascular events by reducing plasma cholesterol levels, and practice guidelines for patients with known cardiovascular disease emphasize … sjmc houston texasWebMar 18, 2024 · A number of statins are available for use in the United States. They include: Atorvastatin (Lipitor) Fluvastatin (Lescol XL) Lovastatin (Altoprev) Pitavastatin (Livalo, Zypitamag) Pravastatin (Pravachol) Rosuvastatin (Crestor, Ezallor) Simvastatin (Zocor) Sometimes, a statin is combined with another heart medication. sjmc medical groupWebOct 2, 2024 · Statin drugs have been shown to reduce the risk of cardiovascular disease (CVD) in young and middle-aged adults. With older adults (those 75 and over), the benefits are less clear. But a recent study published in the European Heart Journal suggests that there is in fact a benefit to statin use in this older population. sjm chelsea hospitalWebFeb 26, 2024 · Based on high-quality evidence from randomized controlled trials (RCTs), high-intensity statin therapy should be instituted with a goal of lowering LDL-C levels by 50% or more in patients with ... sutliff truck centerWebJun 1, 2024 · Design, setting, and participants: This retrospective, population-based cohort study included the 29 047 residents in the Italian Lombardy region aged 65 years or older … sutliff trailer park tustin